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Insect-eP450DB
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Compound
Gene
BLAST
Tree
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Help
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Insecta
Lepidoptera
Noctuidae
Helicoverpa
CYP6AE14
Oganism
Helicoverpa armigera
NCBI Accession
Gene | 110371751
3D Structure
Download
Nucleotide
Protein
3D Structure
7
pairs of Verified P450 and Compound
Validation
Compound
Validation
Reference
Fenvalerate
X
Phylogenetic and functional characterization of ten P450 genes from the CYP6AE subfamily of Helicoverpa armigera involved in xenobiotic metabolism
Insect Biochemistry and Molecular Biology
2018/12/28 | 10.1016/j.ibmb.2017.12.006 | WOS:000427100600009
PubMed Link
Gossypol
R
Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypol
Nature Biotechnology
2007/11/1 | 10.1038/nbt1352 | WOS:000251086500032
PubMed Link
Gossypol
Y
Effect of a functional recombinant cytochrome P450 enzyme of Helicoverpa armigera on gossypol metabolism co-expressed with NADPH-cytochrome P450 reductase in Pichia pastoris
Pesticide Biochemistry and Physiology
2019/4/5 | 10.1016/j.pestbp.2019.01.003 | WOS:000462265000003
PubMed Link
Methoxsalen
C,X
CYP6AE gene cluster knockout in Helicoverpa armigera reveals role in detoxification of phytochemicals and insecticides
Nature Communications
2018/11/16 | 10.1038/s41467-018-07226-6 | WOS:000450273500007
PubMed Link
2-Tridecanone
C,X
CYP6AE gene cluster knockout in Helicoverpa armigera reveals role in detoxification of phytochemicals and insecticides
Nature Communications
2018/11/16 | 10.1038/s41467-018-07226-6 | WOS:000450273500007
PubMed Link
Aldrex
X
Phylogenetic and functional characterization of ten P450 genes from the CYP6AE subfamily of Helicoverpa armigera involved in xenobiotic metabolism
Insect Biochemistry and Molecular Biology
2018/12/28 | 10.1016/j.ibmb.2017.12.006 | WOS:000427100600009
PubMed Link
Imidacloprid
X
Phylogenetic and functional characterization of ten P450 genes from the CYP6AE subfamily of Helicoverpa armigera involved in xenobiotic metabolism
Insect Biochemistry and Molecular Biology
2018/12/28 | 10.1016/j.ibmb.2017.12.006 | WOS:000427100600009
PubMed Link