CYP6AB12

Oganism	Spodoptera litura
NCBI Accession	Nucleotide \| MH644187.1
3D Structure
Download	Nucleotide Protein 3D Structure

4 pairs of Verified P450 and Compound

Compound	Validation	Reference
Cypermethrin	R	Copper exposure enhances Spodoptera litura larval tolerance to β-cypermethrin Pesticide Biochemistry and Physiology 2019/10/9 \| 10.1016/j.pestbp.2019.07.010 \| WOS:000487571100015 PubMed Link
Gossypol	R	Knockdown of cytochrome P450 gene CYP6AB12 based on nanomaterial technology reduces the detoxification ability of Spodoptera litura to gossypol Pesticide Biochemistry and Physiology 2023/1/23 \| 10.1016/j.pestbp.2022.105284 \| WOS:000908320300004 PubMed Link
lambda-CYHALOTHRIN	R	Activation of CncC pathway by ROS burst regulates cytochrome P450 CYP6AB12 responsible for λ-cyhalothrin tolerance in Spodoptera litura Journal of Hazardous Materials 2020/3/16 \| 10.1016/j.jhazmat.2019.121698 \| WOS:000514758500068 PubMed Link
Cyantraniliprole	R,D	Inducible Cytochrome P450s in the Fat Body and Malpighian Tubules of the Polyphagous Pests of Spodoptera litura Confer Xenobiotic Tolerance Journal of Agricultural and Food Chemistry 2023/10/14 \| 10.1021/acs.jafc.3c04865 \| WOS:001076214300001 PubMed Link