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Insect-eP450DB
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For technical assistance, please contact:




Ziqi Cheng, chengziqi1004@163.com
Yang Mei, yang_mei1012@163.com

  • Insecta
  • Diptera
  • Culicidae
  • Anopheles

CYP6M2


Oganism Anopheles gambiae
NCBI Accession Gene | 5668319
3D Structure
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Nucleotide Protein 3D Structure

4 pairs of Verified P450 and Compound


Compound Validation Reference
Compound Image
Pyriproxyfen
E
  • Pyriproxyfen is metabolized by P450s associated with pyrethroid resistance in An. gambiae
  • Insect Biochemistry and Molecular Biology
  • 2016/11/1 | 10.1016/j.ibmb.2016.09.001 | WOS:000388053200006
  • PubMed Link
Compound Image
Clofenotane
X
  • Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana
  • Proceedings of The National Academy of Sciences of The United States of America
  • 2012/4/17 | 10.1073/pnas.1203452109 | WOS:000303246100052
  • PubMed Link
Compound Image
Permethrin
E
  • Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed
  • Insect Biochemistry and Molecular Biology
  • 2011/7/1 | 10.1016/j.ibmb.2011.02.003 | WOS:000293041200010
  • PubMed Link
Compound Image
Deltamethrin
E
  • Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed
  • Insect Biochemistry and Molecular Biology
  • 2011/7/1 | 10.1016/j.ibmb.2011.02.003 | WOS:000293041200010
  • PubMed Link

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