Capsaicin


PubChem CID 1548943
Molecular Formula C18H27NO3
Structure Compound Image
Synonyms
Capsaicin
404-86-4
(E)-Capsaicin
Zostrix
CAPSAICINE
Qutenza
Styptysat
Axsain
trans-Capsaicin
Isodecenoic acid vanillylamide
Ausanil
E-CAPSAICIN
Mioton
NGX-4010
trans-8-Methyl-N-vanillyl-6-nonenamide
FEMA No. 3404
Dolenon
Ovocap
(E)-8-Methyl-N-vanillyl-6-nonenamide
Capzasin-hp
Caswell No. 158
Togarashi orenji
ALGRX 4975
C18H27NO3
Ratden pe 40
NCI-C56564
NSC 56353
Capsaicinoid
CCRIS 1588
CHEBI:3374
HSDB 954
Transacin
(e)-n-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide
Zostrix HP
NGX-1998
EINECS 206-969-8
UNII-S07O44R1ZM
MFCD00017259
NSC-56353
(6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide
EPA Pesticide Chemical Code 070701
N-(4-Hydroxy-3-methoxybenzyl)-8-methylnon-trans-6-enamide
8-Methyl-N-vanillyl-trans-6-nonenamide
BRN 2816484
S07O44R1ZM
DTXSID9020241
Capsaicin (JAN/USP)
6-Nonenamide, 8-methyl-N-vanillyl-, (E)-
NSC56353
ZOSTRIX (TN)
Cntx-4975
(6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (6E)-
DTXCID30241
7553-53-9
ALGRX-4975
CHEMBL294199
1217899-52-9
(E)-N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE
6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (E)-
Capsaicin [in oleoresin of capsicum]
N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide
trans-Capsaicin-d3
NCGC00017337-02
Capsaicin (USP:INN)
Capsaicin [USP:INN]
8-Methyl-N-vanillyl-(trans)-6-nonenamide
Capsaicin(E/Z-Mixture)
(E)-N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamide
(E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide
6-Nonenamide, (E)-N-((4-hydroxy-3-methoxy-phenyl)methyl)-8-methyl
6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (E)-
CAPSAICIN (MART.)
CAPSAICIN [MART.]
CAPSAICIN (USP-RS)
CAPSAICIN [USP-RS]
Capsaicin [USAN]
CAPSAICIN (USP MONOGRAPH)
CAPSAICIN [USP MONOGRAPH]
Capsicine
Zacin
Capsaicin Patch
Capsaicin (in oleoresin of capsicum)
(6E)-N-{[4-hydroxy-3-(methyloxy)phenyl]methyl}-8-methylnon-6-enamide
6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (6E)-
NGX 4010
8-Methyl-N-Vanillyl-6-Nonenamide
SR-05000001861
capsaicinum
neurotoxic
Capsaicina
Isodecenoate
Zucapsaicin;Civamide;cis-Capsaicin
Capsacin
Capsimide
N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
Neuriterx
Neuritrx
Adlea
Awaye
8-Methyl-N-vanillyl-6-nonenamide, (E)-
BioMega
TNP00277
Ageranium Patch
Capsaicin Cream
Capsaicin Heat
Castiva Warming
Guardania Pain
Medicated Heat
Rugby Capsaicin
(E)-N-[(4-Hydroxy-3-methoxyphenyl)-methyl]-8-methyl-6-nonenamide
Satogesic Hot
MediRelief Hot
SprayPain Away
epsilon-capsaicin
Pure Relief
CVS Capsaicin
Painazin CP
Bio-Sorb
capsacin(E)
Capsaicin Extract
NobleAid CapsAid
Qutenza;Vanilloid
Melt Pain Away
Red Hot
PainBloc24
Capsaicin,(S)
Nufabrx Back Wrap
Nufabrx Neck Wrap
Gellert Joint Care
Nufabrx Arm Sleeve
4DY
CAS-404-86-4
Omega 3
Prestwick_204
CVS Roll-On
Nufabrx Calf Sleeve
Nufabrx Knee Sleeve
Capsaicin (Natural)
Capsaicin 0.15
Capsaisin 0.1%
depletes Substance P
LivReliefPain Relief
CAPSAISIN
CAPZIX
Nufabrx Ankle Sleeve
Nufabrx Wrist Sleeve
REZIL
FlexxSonicPain Relief
Hot SpotPoint Relief
Capsaicin 0.05%
Capsaicin 0.15%
Capsaicin 0.25%
Capsaicin Pain Relief
Rugby Capsaicin Cream
capsaicin 0.075%
LEADER CAPSAICIN
MEIJER CAPSAICIN
A2A ARTHRITIS
Coralite Medicated Heat
HOT PAIN RELIEF
RETADOLORPain Relief
Sure Relief SR Relief
Sure Result SR Relief
Walgreens Capsaicin Hot
starbld0019180
Campo pharma Muscle hot
CAPSAICIN [INN]
CAPSAICIN [JAN]
Capsaicin 0.1 Percent
CAPSAICIN [MI]
6-Nonenamide, (E)-
EQUI-BLOCKORIGINAL
CAPSAICIN [HSDB]
Nufabrx Lower Leg Sleeve
Prestwick2_000879
Prestwick3_000879
Spectrum5_000538
Zostrix Original Strength
CAPSAICIN [VANDF]
CAPSAICIN, NATURAL
CapsaicinTopical Analgesic
QC Arthritis Pain Relief
SCREAMIN HOT TOAST
Wellness Products VictoRx
CapsaicinExternal Analgesic
Medicated Compression Sock
N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, (E)-
Nufabrx Foot/Ankle Sleeve
Nufabrx Hand/Wrist Sleeve
Wellness Products J-FLEX
CVS Medicated Heat 1 ct
SINSINPAS HOT LARGE
2-Count HEAT PATCHES
UPCMLD-DP092
Capsaicin 0.075 Percent
EQUI-BLOCKDT FORMULA
CAPSAICIN [WHO-DD]
SCHEMBL8085
SCHEMBL8086
CANNAVERA PAIN RELIEF
CAPSAICIN HOT PATCHES
EARTHS CARE ARTHRITIS
MR3H3
Revlex Arthritis Pain Relief
Solstice Capsaicin Patch Hot
BSPBio_000957
BSPBio_001548
BSPBio_002917
CAPSAICIN [EMA EPAR]
CareALL Arthritis and Muscle
RITE AID CAPSICUM HOT
MLS002154049
N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide
ASTRAPHARM CHILLI BRAND
Capsaicin from Capsicum annuum
Capsaicin, analytical standard
SPECTRUM1501128
WellPatch Warming Pain Relief
BRONSON SOOTHE Pain Relief
FYZICAL SPORTS Pain Relief
Nufabrx Medicine Infused Socks
Rugby Arthritis Pain Relieving
6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-
Nufabrx Lower Leg Sleeve M/L
BPBio1_001053
Equate Capsaicin Pain Relieving
GTPL2486
HURT BLOCKER PROPain Relief
MEGxp0_001448
CAPSAICIN [ORANGE BOOK]
Nufabrx Lower Leg Sleeve XS/S
6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (6Z)-
Good Neighbor Pharmacy Capsaicin
UPCMLD-DP092:001
UPCMLD-DP092:002
BDBM20461
BDBM86537
Better Nature Pain Relief BalmX
CHEBI:94524
Fast Arthritis AidPain Relieving
HMS501B16
Rugby CapsaicinExternal Analgesic
Sherman and Clark Pain Relieving
Family Care Arthritis Pain Relief
Nufabrx Lower Leg Sleeve XL/XXL
Capsaicin 0.025% Topical Patch
Capzasin HP Arthritis Pain Relief
HMS1361N10
HMS1570P19
HMS1791N10
HMS1921H11
HMS1989N10
HMS2089N11
HMS2092D21
HMS2097P19
HMS2230O23
HMS3402N10
HMS3414F11
HMS3649N15
HMS3678F11
Penetrex(r) Arthritis Pain Relief
Pharmakon1600-01501128
Pure ReliefPenetrating Pain Relief
Capsaicin HP Arthritis Pain Relief
Frankie Avalons Zero Pain Roll On
Leader Capsaicin Pain Relief Cream
8-Methyl-N-vanillyl-6E-nonenamide
AMY25669
beeRX Muscle and Joint Pain Relief
CVS Capsaicin arthritis pain relief
DCH Arthritis Pain Relief Roll-On
NGX-3781
NGX-7325
NSC_2548
Miracle Plus OvernightPain Relieving
Tox21_110817
Tox21_200315
BBL027836
CCG-39657
CCG-39908
EI-125
HB1179
HY-10448A
LMFA08020085
NSC757844
s1990
STL372889
Toplast Hot Capsaicin 0.025percent
Nufabrx Medicine Infused Ankle Sleeve
(E)8-methyl-N-vanillyl-6-Nonenamide
AKOS007930159
AVON HeXashield Arthritis Pain Relief
Zostrix High Potency Foot Pain Relief
(6E)-N-
CS-1518
DB06774
FYZICAL SPORTS Pain Relief 2 MILD
KS-5181
NSC-757844
SDCCGMLS-0066678.P001
TQ-1018
Capsaicin 10 microg/mL in Acetonitrile
Capsaicin, >=95%, from Capsicum sp.
Dr. Harveys Herbal Motion Pain Formula
IDI1_000354
IDI1_034018
SMP2_000337
NCGC00017337-03
NCGC00017337-04
NCGC00017337-05
NCGC00017337-06
NCGC00017337-07
NCGC00017337-08
NCGC00017337-09
NCGC00017337-10
NCGC00017337-11
NCGC00017337-12
NCGC00017337-13
NCGC00017337-17
NCGC00017337-18
NCGC00090853-01
NCGC00090853-02
NCGC00090853-03
NCGC00090853-04
NCGC00090853-06
NCGC00090853-07
NCGC00090853-08
NCGC00090853-09
NCGC00090853-10
NCGC00090853-11
NCGC00090853-12
NCGC00257869-01
USEPA/OPP Pesticide Code: 070701
AC-10114
CAPSAICIN HEAT PATCHES PAIN RELIEF
CAS_404-86-4
HY-10448
LS-14673
SMR000718774
CAPSAICIN (CONSTITUENT OF CAPSICUM)
SBI-0052593.P002
Dusel Warm Arthritis Dead Sea Salt Therapy
CS-0181240
Good Neighbor Capsaicin Heat Patch for Back
M1149
NS00004284
(E)-8-Methyl-N-vanillyl-6-nonenamide(8cl)
C-1700
C06866
D00250
Rugby Arthritis Pain RelievingTopical Analgesic
AB00053098-11
AB00053098_12
ASTRAPHARM CHILLI BRAND EXTERNAL MEDICATED
Capsaicin, from Capsicum sp., >=50% (HPLC)
EN300-7544118
826 - Capsaicin and heat units in chilli powder
CAPSAICIN (CONSTITUENT OF CAPSICUM) [DSC]
CAPSAICIN HEAT PATCHES BACK AND LARGE AREAS
Q273169
AVON HeXashield Arthritis Pain ReliefCream Capsaisin
Hempvana Ultra Strength Pain Relief Cream-Deep Heat
SR-05000001861-1
SR-05000001861-4
SR-05000001861-5
SR-05000001861-6
SR-05000001861-9
Walgreens Arthritis Pain Relief Capsaicin Analgesic
BRD-K37056290-001-01-1
BRD-K50590187-001-06-6
BRD-K50590187-001-19-9
BRD-K50590187-001-20-7
Capsaicin, certified reference material, TraceCERT(R)
Flavor and Extract Manufacturers' Association No. 3404
Capsaicin, European Pharmacopoeia (EP) Reference Standard
(6E)-N-(4-Hydroxy-3-methoxybenzyl)-8-methyl-6-nonenamide #
Capsaicin, United States Pharmacopeia (USP) Reference Standard
Capsaicin; 8-Methyl-N-vanillyl-trans-6-nonenamide; NGX-4010
N-[(4-hydroxy-3-methoxyphenyl)methyl]-6E-8-methyl-nonenamide
N-(4-HYDROXY-3-METHOXYBENZYL)-8-METHYL-6-NONENAMIDE [FHFI]
trans-N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide
6-nonenamide,n-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-,(6e)-
Capsaicin, Pharmaceutical Secondary Standard; Certified Reference Material

Computed Descriptors


IUPAC Name (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
SMILES CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC
Canonical SMILES CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
InChI InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
InChIKey YKPUWZUDDOIDPM-SOFGYWHQSA-N

Computed Properties

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Molecular Weight 305.4 g/mol
XLogP3 3.6
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 9
Exact Mass 305.199
Monoisotopic Mass 305.199
Topological Polar Surface Area 58.6
Heavy Atom Count 22
Formal Charge 0
Complexity 341
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1

Annotation

  • C78272 - Agent Affecting Nervous System
  • C241 - Analgesic Agent
  • C2198 - Nonnarcotic Analgesic|D003879 - Dermatologic Agents
  • D000982 - Antipruritics|D018373 - Peripheral Nervous System Agents
  • D018689 - Sensory System Agents|M - Musculo-skeletal system
  • M02 - Topical products for joint and muscular pain
  • M02A - Topical products for joint and muscular pain
  • M02AB - Capsaicin and similar agents|N - Nervous system
  • N01 - Anesthetics
  • N01B - Anesthetics, local
  • 4 pairs of Verified P450 and Capsaicin


    Insect Gene Symbol Validation Reference
    Helicoverpa armigera CYP6B6 E
    Helicoverpa armigera CYP9A12 E
    Helicoverpa armigera CYP9A14 E
    Helicoverpa armigera CYP9A17 E